This study presents SynaptoGen, a differentiable extension of connectome models that links gene expression, protein-protein interaction probabilities, synaptic multiplicity, and synaptic weights, and ...

In pursuit of better ways to test new therapies and further explore the impacts of the unique genetics associated with Down syndrome, researchers at Johns Hopkins Medicine and Tottori University in ...

Researchers compared a new genetic animal model of Down syndrome to the standard model and found the updated version to be enhanced. The new mouse model shows milder cognitive traits compared to a ...

One of the greatest challenges biologists face is figuring out which of the myriad variations in a person’s genetic code might make them sick. Artificial intelligence is helping them solve the problem ...

A novel genetic model suggests that the ancestors of modern humans came from two distinct populations that split and reconnected during our evolutionary history. When you purchase through links on our ...

An illustration of the genetic and expression map of the PWS critical region (15q11-q13). This figure illustrates the genomic structure of the PWS critical region on chromosome 15, showing the ...