Crofelemer has been granted Orphan Drug Designation by the U.S. Food and Drug Administration (FDA) and the European Medicines Agency for SBS and MVID. In October 2025, as announced, the company ...

King Faisal Specialist Hospital & Research Centre continues to advance complex transplant medicine through its Intestinal Transplant Program, a highly specialized service designed to manage patients ...

Jaguar Health (JAGX) announced that an article published December 29, 2025 in HEALTH, a bi-monthly English and Arabic healthcare magazine in the ...

Intestinal stem cells (ISCs) derived from a patient's own cells have garnered significant attention as a new alternative for ...

SBS-IF is the second orphan disease target indication for Jaguar’s intestinal failure program, which includes microvillus inclusion disease (MVID) – for which the company completed a meeting in ...

Intestinal failure is defined as having an intestinal condition which renders a child unable to maintain adequate hydration and meet calorie absorption needs sufficient for growth. This results in ...

The Glennon Intestinal Rehabilitation and Feeding (GIRAF) program was established in 2015 as the first multidisciplinary program of its kind in the region dedicated to the specific needs of pediatric ...

Specifically, the team confirmed that increased expression of cytoskeleton-binding and actin-binding proteins leads to a stable restructuring of the internal cellular architecture. This provides the ...

A recent study sheds light on what predisposes premature infants to necrotizing enterocolitis (NEC), a deadly intestinal disease. Currently, there are no targeted treatments for NEC because the causes ...

The terms "intestinal barrier" and "intestinal permeability" describe two different aspects of the same anatomical structure, the intestinal wall composed of four layers, the mucosa, the submucosa, ...