Scientists have discovered that T cell receptors activate through a hidden spring-like motion that had never been seen before. This breakthrough may help explain why immunotherapy works for some ...

Enhanced Signal-to-Noise Ratio as a Primary Advantage of MBLI Tetramers Concerning Biological Interactions with Dextran. In this blog, we will discuss the increasing evidence in the literature and ...

The gray portion of this schematic represents a nanodisc, where for the first time researchers were able to replicate the native membrane environment (red dots) of a T-cell receptor (cyan). One of the ...

Tecelra is a novel class of engineered autologous T-cell therapies that target the cancer germline antigen MAGE-A4, which is expressed in several tumors but missing in healthy tissues. Unlike chimeric ...

An engineered protein turns off the kind of immune cells most likely to damage tissue as part of Type-1 diabetes, hepatitis, multiple sclerosis, shows a new study in mice. In these autoimmune diseases ...

One of the most exciting advances in cancer treatments in the past decade is the development of T cell immunotherapies, in which a patient's own immune system is trained to recognize and attack ...