Neurofibromatosis type 2 is caused by a change in the NF2 gene located on chromosome 22. This gene encodes a protein known as merlin. Mutations in the NF2 gene disrupt the function of merlin, which is ...
It’s important to know that an accurate diagnosis of NF2 can only be made by a physician with expertise in the diagnosis and treatment of neurofibromatosis. Specific diagnostic criteria have been ...
ORLANDO, Fla. ― The first-in-class YAP/TEAD inhibitor VT3989 was well tolerated with durable antitumor responses in patients with advanced malignant mesothelioma and other tumors with NF2 mutations, ...
Neurofibromatosis type 2 (NF2) is an autosomal‐dominant disorder characterised by the development of multiple tumours, most notably bilateral vestibular schwannomas. These benign tumours originate ...
Overall Survival With Maintenance Olaparib at a 7-Year Follow-Up in Patients With Newly Diagnosed Advanced Ovarian Cancer and a BRCA Mutation: The SOLO1/GOG 3004 Trial Eligible patients whose tumors ...
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