CLEVELAND - Researchers at the Case Western Reserve University School of Medicine have identified a cellular mechanism that is critical in maintaining normal cell function. In their work, the ...

Researchers have identified a cellular mechanism that is critical in maintaining normal cell function. They examined the function of TRAMP, a protein complex involved in the processing of RNA or ...

The conserved Saccharomyces cerevisiae Ski2-like RNA helicase Mtr4p plays essential roles in eukaryotic nuclear RNA processing. RNA helicase activity of Mtr4p is critical for biological functions of ...

Eukaryotic cells have to prevent the export of unspliced pre-mRNAs until intron removal is completed to avoid the expression of aberrant and potentially harmful proteins. Only mature mRNAs associate ...